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1. Examining Regeneration Capacity and Innervation of NMJs by iPSC-Derived Motor Neurons

By: Katherine Marshall

Additional Authors: Madison James, Labchan Rajbhandari, Arens Taga, Arun Venkatesan, Nicholas Maragakis, Mohamed Farah

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2. Clinical and genetic complexity among patients with the progressive mitochondrial neurodegenerative disease LHON-Plus

By: Anne Chiaramello

Additional Authors: Andrea Gropman, Eliana Gropman, Lisa Thompson, Martine Uittenbogaard

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3. Pharmacokinetics, Food Effect & Relative Bioavailability of Two Formulations of NBI-921352/XEN901 in Healthy Adults: Pediatric Granules & Adult Tablets

By: Gregory Beatch

Additional Authors: Rostam Namdari, Jay A. Cadieux, Gordon Loewen, Ernesto Aycardi

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4. Potential Drug-Drug Interactions Between NBI-921352/XEN901 (a Novel Nav1.6 Selective Sodium Channel Blocker) and a Strong Inducer of CYP3A4 (Phenytoin) in Healthy Volunteers 

By: Gordon Loewen

Additional Authors: Gregory Beatch, Jay Cadieux, Rostam Namdari, Ernesto Aycardi

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5. Utilizing Human Subjects Research Protection Trainings and Site Initiation Visits to Improve Participant Safety in Clinical Neurology Research

By: Matthew Gooden

Additional Authors: Gina Norato, Sandra Martin, Lauren Reoma

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6. Safety and Pharmacokinetics of Antisense Oligonucleotide STK-001 in Children and Adolescents with Dravet Syndrome: Design of the Open-Label Phase 1/2a MONARCH Study 

By: Javier Avendaño

Additional Authors: Linda Laux, Charlene Brathwaite, James Stutely, Nancy Wyant, Kimberly Parkerson, Barry Ticho

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7. NIH HEAL Initiative: NINDS Preclinical Screening Platform for Pain (PSPP) 

By: Sarah Woller

Additional Authors: Amir Tamiz, Mark Urban, Mark Varney, Emer Leahy, Taleen Hanania, Smriti Iyengar

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9. Establishment of a reversal learning assay in rats to investigate the effects of novel compounds on executive function

By: Fionn Dunphy-Doherty

Additional Authors: Danka Kozareva, Ewa Sokolowska , Jack Prenderville

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10. The NINDS Ultra-Rare Gene-based Therapy network: An URGenT need for ultra-rare neurological diseases

By: Ann-Marie Broome

Additional Authors: Nina Schor, Amir Tamiz, Jill Morris, Chris Boshoff, Mario Skiadopoulos, Julia Bachman, Genevieve Lind, Walter Koroshetz

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11. Efficacy & Safety of AXS-05, an Oral, NMDA Receptor Antagonist with Multimodal Activity in Major Depressive Disorder: Results from the ASCEND Phase 2, Double-blind, Active-controlled Trial

By: Amanda Jones

Additional Authors: Cedric O'Gorman, Mark Jacobson, Dan Iosifescu, Herriot Tabuteau

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12. Efficacy and Safety of AXS-05, an Oral, NMDA Receptor Antagonist with Multimodal Activity in Major Depressive Disorder: Results from the GEMINI Phase 3, Double-Blind, Placebo-Controlled Trial

By: Cedric O’Gorman

Additional Authors: Amanda Jones, Dan Iosifescu, Herriot Tabuteau

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13. Functional and Long-Term Survival Data of AMX0035 in Amyotrophic Lateral Sclerosis: Results of the CENTAUR Trial

By: Sabrina Paganoni

Additional Authors: Sean Healey,  Suzanne Hendrix, Samuel Dickson, Newman Knowlton, Joshua Cohen, Justin Klee, Kent Leslie, Rudolph Tanzi, Patrick Yeramian, Merit Cudkowicz

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14. GM6 attenuates inflammation in Alzheimer’s disease pathology concurrently with reducing Beta Amyloid and phosphorylated tau

By: Mark Kindy

Additional Authors: Dorothy Ko

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15. AlzPED: Optimizing the Predictive Power of Drug Efficacy Studies in Alzheimer’s Disease Animal Models

By: Shreaya Chakroborty

Additional Authors: Ali Sharma, Zane Martin, Jean Yuan, Suzana Petanceska, Lorenzo Refolo

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16. Modulation of the p38 MAPK Pathway in Peripheral Blood Mononuclear Cells: Implications for Screening Novel Anti-Inflammatories in Alzheimer’s Disease 

By: Luke Davison

Additional Authors: Davison L, Duggan S, Downer E.J.,  Prenderville J.A.

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17. Dimethyl fumarate suppresses neurodegeneration through reduction of M1 macrophages-induced A1 reactive astrocytes and complement C3 deposition 

By: Sudhir Kumar Yadav

Additional Authors: Naoko Ito,  Devika Soin,  Kouichi Ito,  Suhayl Dhib-Jalbut

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18. Development of a Reconstituted Assay to Test Casein Kinase 1δ Inhibitors to Block Alzheimer’s Disease Progression 

By: Sabyasachi Chatterjee

Additional Authors: Angel’Niqua Dixon, Linh Tran, Breyanah Graham, Jumia Callaway, Phong Huynh, Jayalakshmi Sridhar, Thomas Huckaba

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19. Evaluation of novel non-opioid, non-addictive pain therapeutics within the NIH HEAL Initiative PSPP program- a case study 

By: Smriti Iyengar

Additional Authors:  Amir Tamiz,  Taleen Hanania, Emer Leahy, David Budac, Elizabeth Dugan, Mark Urban, Daniela Brunner, Herman Fernandes, Jodi Gresack, Qing Chang, Mark Varney, Sarah A. Woller

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20. Depression and Anhedonia: Acute Preclinical Efficacy for XEN1101, a Differentiated Kv7 Potassium Channel Modulator 

By: Alison Cutts

Additional Authors: Rostam Namdari, Greg Beatch, Nina Weishaupt, Richard Dean, Jeff Bechard, JP Johnson, James Empfield, Robin Sherrington

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21. Anticonvulsant Effects of the Differentiated Kv7 Channel Potentiator XEN1101 in Combination with Commonly Used Anti-Seizure Drugs

By: J.P. Johnson

Additional Authors: Girish Bankar, Celine Dube, Parisa Tari, Karen Nelkenbrecher, Matthew Waldbrook, Nina Weishaupt, Gregory Beatch, Jeff Bechard, Rostam Namdari, Robin Sherrington, Alison Cutts, Charles Cohen, James Empfield

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22. The neutral sphingomyelinase 2 inhibitor PDDC reduces tau burden in Alzheimer’s disease mice

By: Carolyn Tallon

Additional Authors: Benjamin J. Bell, Medhinee Malvankar, Tawnjerae Joe, Kristen R. Hollinger, Ajit G. Thomas, Amrita Datta Chaudhuri, Ying Wu, Rana Rais, Norman J. Haughey, Barbara S. Slusher

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23. Sleep Disturbances in EcoHIV-infected Mice

By: Ben Bell

Additional Authors: Joshua Woo, Xiaolei Zhu, David Volsky, Mark Wu, Barbara Slusher

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24. Modulation of TREM2 Mechanism as a potential treatment for neurodegenerative diseases

By: Rafael Nir

Additional Authors:  Eliezer Zomer,  Olga Volpert,  Erez Eitan,  Elizabeth Griffith

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25. Targeted Inhibition of CDK5-mediated Regulation of Human Endogenous Retrovirus K Envelope Protein in Atypical Teratoid Rhabdoid Tumor 

By: Tara Doucet-O'Hare

Additional Authors: Jared Rosenblum,  Brianna DiSanza, Catherine DeMarino, Nasir Malik,  Joseph Steiner,  Abigail Atkinson,  Harish Pant,  Zhengping Zhuang,  Avindra Nath

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26. Neurophysiological Biomarkers of Dorsal and Ventral Subthalamic Nucleus in Parkinson’s Patients 

By: Jeffrey Nie

Additional Authors: Ahmad Elkouzi

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27. Impact of Neuregulin 1 Type III overexpression on motor axon development in Spinal Muscular Atrophy (SMA) model mice

By: Jeffrey Petigrow

Additional Authors: Cera Hassinan,  Lingling Kong, Michelle Harren Chan-Cortes,  Jannick Büttner,  Christian M. Simon,  Charlotte Sumner

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28. NINDS/Division of Translational Research-Funded Drug Discovery and Development Programs 

By: Mohamed Hachicha

Additional Authors: Charles Cywin, Amir Tamiz

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29. Securing bench to bedside translation with predictive EEG biomarkers of Parkinson's Disease

By: Venceslas Duveau

Additional Authors: Julien Volle, Chloé Habermacher, Alexis Evrard, Hedi Gharbi, Corinne Roucard, Yann Roche

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30. EEG Phenotyping as a tool to develop preclinical rodent models of brain disorders for identification and validation of new Neurotherapeutics

By: Corinne Roucard

Additional Authors: Venceslas Duveau, Julien Volle, Chloé Habermacher, Céline Ruggiero, Alexis Evrard, Yann Roche

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31. An fMRI study for discovering the resting-state functional changes in Schizophrenia using a statistical and ML-based approach 

By: Indranath Chatterjee

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32. Toward the use of paramagnetic rim lesions in proof-of-concept clinical trials for treating chronic inflammation in multiple sclerosis 

By: Jemima Akinsanya

Additional Authors: Martina Absinta, Nigar Dargah-zade, Erin S. Beck, Hadar Kolb,  Omar Al-Louzi, Pascal Sati, Govind Nair, Gina Norato, Karan D. Kawatra, Jenifer Dwyer, Rose Cuento, Frances Andrada, Joan Ohayon, Steven Jacobson, Irene Cortese, Daniel S. Reich

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33. Optimizing Tilorone Analogs as Acetylcholinesterase Inhibitors Using Machine Learning and Recurrent Neural Networks

By: Ana Puhl

Additional Authors: Patricia A. Vignaux,  Eni Minerali,  Thomas R. Lane,  Daniel H. Foil,  Kimberley M. Zorn,  Fabio Urbina,  Jeremiah P. Malerich,  Dominique A. Tartar,  Peter B. Madrid,  Sean Ekins

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34. Combined TMS/MRI with deep brain stimulation capability 

By: Dr. Irving Weinberg

Additional Authors: Oleg Udalov, Irving N. Weinberg, Ittai Baum, Cheng Chen, XinYao Tang, Micheal Petrillo, Roland Probst, Chase Seward, Sahar Jafari,  Pavel Y. Stepanov, Anjana Hevaganinge, Olivia Hale, Danica Sun, Edward Anashkin, Lamar O. Mair,  Elaine Y. Wang,  David Ariando,  Soumyajit Mandal,  Alan McMillan,  Mirko Hrovat,  Stanley T. Fricke

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35. The CURE Epilepsy Catalyst Award: Grant Opportunity For Translational Research in Epilepsy

By: Priya Balasubramanian

Additional Authors: Laura Lubbers

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36. Academic and Industry Physician Workforce Development in Experimental Neurotherapeutics

By: Shih Ludy

Additional Authors: Dietrich Haubenberger

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